| Myocardial contractile reserve as prognostic determinant in patients with idiopathic dilated cardiomyopathy without overt heart failure. | |
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MedLine Citation:
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PMID: 9041980 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To assess the prognostic significance of myocardial contractile reserve in patients with idiopathic dilated cardiomyopathy (DCM) without overt heart failure (New York Heart Association functional class I or II), seventy-one patients underwent exercise radionuclide angiography in addition to clinical, radiographic, hemodynamic, and echocardiographic evaluations. Myocardial contractile reserve was assessed as left ventricular ejection fraction (LVEF) during peak exercise minus LVEF at rest (delta LVEF). During an average of 49 months, 18 patients died of the disease. Cox's proportional-hazards regression analysis showed that the delta LVEF was the most powerful and independent discriminator for survival (p = 0.0002). Ejection time (p = 0.0029) and cardiothoracic ratio (p = 0.017) were the second and third most predictive variables, respectively. Evaluation of the delta LVEF, which reflects residual myocardial contractile reserve, can provide important information about the prognosis of patients with DCM and mild symptoms. |
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Authors:
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H Nagaoka; N Isobe; S Kubota; T Iizuka; S Imai; T Suzuki; R Nagai |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Chest Volume: 111 ISSN: 0012-3692 ISO Abbreviation: Chest Publication Date: 1997 Feb |
Date Detail:
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Created Date: 1997-03-21 Completed Date: 1997-03-21 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0231335 Medline TA: Chest Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 344-50 Citation Subset: AIM; IM |
Affiliation:
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Second Department of Internal Medicine, Gumna University School of Medicine, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Cardiomyopathy, Dilated / mortality, physiopathology* Exercise Test Female Humans Male Middle Aged Myocardial Contraction Prognosis Proportional Hazards Models Radionuclide Angiography Stroke Volume* Survival Rate Ventricular Function, Left* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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