Document Detail


Myocardial capillaries in guinea pigs native to high altitude (Junin, Peru, 4,105 m).
MedLine Citation:
PMID:  7279597     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Quantitative evaluation of the myocardial left ventricular capillarity was performed in three groups of guinea pigs: a) animals native to high altitude collected in Andean mountains, b) animals born at sea level and subjected to a stimulated high altitude postnatally, c) animals born and kept at sea level. The number of capillaries and muscle fibers/mm(2) as well as the fiber capillary ratio and the diffusion distance were similar in all three experimental groups. The only difference found during the detailed analysis of the myocardial capillarity was a slightly lower percentage of the myocardial tissue in the extreme distance from the capillary found in the hearts of high altitude natives when compared to sea level animals. From these morphometric data the distribution of diffusion distances was derived which can be approximated by lognormal distribution. Capillary inhomogeneity expressed as log standard deviation was found to be similar in all three groups.
Authors:
K Rakuŝan; Z Turek; F Kreuzer
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pflügers Archiv : European journal of physiology     Volume:  391     ISSN:  0031-6768     ISO Abbreviation:  Pflugers Arch.     Publication Date:  1981 Jul 
Date Detail:
Created Date:  1981-11-18     Completed Date:  1981-11-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0154720     Medline TA:  Pflugers Arch     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  22-4     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adaptation, Physiological
Altitude*
Animals
Capillaries / physiology*
Coronary Vessels / physiology*
Guinea Pigs
Peru

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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