| Myocardial blood flow parameters derived from contrast replenishment using harmonic power Doppler imaging are underestimated by ultrasound signal attenuation. | |
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MedLine Citation:
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PMID: 12835660 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effect of ultrasound signal attenuation on myocardial blood flow parameters derived from contrast replenishment was evaluated using harmonic gray-scale (HGS) and harmonic power Doppler (HPD) imaging. In vitro experiments were performed in a flow model, whereas in vivo experiments were performed in 5 open-chest dogs. In each study, intermittent HGS and HPD images were acquired at various pulsing intervals during contrast infusion. A silicone pad was interposed between the transducer and target region to simulate attenuation conditions. Baseline-subtracted HGS and HPD signal intensities were measured with and without silicone pad, and myocardial blood flow parameters A and beta were calculated using contrast replenishment. Attenuation with HGS images could be offset by baseline subtraction, as baseline images provided the reference for attenuation. However, attenuation with HPD images could not be compensated for, as baseline signal intensity was theoretically 0. In HGS mode, silicone attenuation produced no significant decreases in A and beta. In HPD mode, however, A and beta were significantly decreased by silicone attenuation (A, P <.001; beta, P <.05). Compared with nonattenuated regions, myocardial blood flow parameters in attenuated regions are underestimated when HPD imaging is used. Baseline-subtracted HGS imaging may be useful to compensate for thoracic wall attenuation. |
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Authors:
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Juri Okazaki; Toshihiko Asanuma; Ayako Miki; Hideo Hirayama; Kentaro Otani; Tsutomu Toshida; Akiko Iwata; Fuminobu Ishikura; Shintaro Beppu |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography Volume: 16 ISSN: 0894-7317 ISO Abbreviation: J Am Soc Echocardiogr Publication Date: 2003 Jul |
Date Detail:
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Created Date: 2003-07-01 Completed Date: 2003-10-21 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8801388 Medline TA: J Am Soc Echocardiogr Country: United States |
Other Details:
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Languages: eng Pagination: 738-44 Citation Subset: IM |
Affiliation:
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Department of Medical Physics, School of Allied Health Sciences, Faculty of Medicine, Osaka University, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Contrast Media Coronary Circulation* Dogs Echocardiography, Doppler* / methods Phantoms, Imaging Signal Processing, Computer-Assisted Swine |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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