Document Detail


Myocardial accumulation of iodinated beta-methyl-branched fatty acid analog, [125I](p-iodophenyl)-3-(R,S)-methylpentadecanoic acid (BMIPP), and correlation to ATP concentration--II. Studies in salt-induced hypertensive rats.
MedLine Citation:
PMID:  8448569     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study investigates the possible relationship between myocardial [125I]BMIPP accumulation and ATP concentration, in the salt-induced hypertensive Dahl-strain rats. [125I]BMIPP accumulation in the myocardium was inversely related to the degree of hypertension. On the other hand, ATP levels increased in the myocardium of rats with higher blood pressure showing an inverse relationship with BMIPP accumulation. Further studies are required for elucidating these possible inter-related phenomena.
Authors:
Y Fujibayashi; P Som; Y Yonekura; F F Knapp; N Tamaki; K Yamamoto; J Konishi; A Yokoyama
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Nuclear medicine and biology     Volume:  20     ISSN:  0969-8051     ISO Abbreviation:  Nucl. Med. Biol.     Publication Date:  1993 Feb 
Date Detail:
Created Date:  1993-04-15     Completed Date:  1993-04-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9304420     Medline TA:  Nucl Med Biol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  163-6     Citation Subset:  IM    
Affiliation:
Faculty of Pharmaceutical Sciences, Kyoto University, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adenosine Triphosphate / metabolism*
Animals
Blood Pressure
Chromatography, High Pressure Liquid
Fatty Acids*
Female
Hypertension / chemically induced,  metabolism*
Iodobenzenes / metabolism*,  pharmacokinetics
Myocardium / metabolism*
Rats
Sodium Chloride / adverse effects
Tissue Distribution
Chemical
Reg. No./Substance:
0/Fatty Acids; 0/Iodobenzenes; 116754-87-1/iodofiltic acid; 56-65-5/Adenosine Triphosphate; 7647-14-5/Sodium Chloride

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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