Document Detail

Myocardial Tagging with MR Imaging: Overview of Normal and Pathologic Findings.
MedLine Citation:
PMID:  22977026     Owner:  NLM     Status:  In-Data-Review    
Magnetic resonance tagging is used to evaluate the dynamic deformation of lines or grids superimposed on the myocardium during the cardiac cycle. From these data, a specific postprocessing procedure provides two kinds of metrics: (a) three orthogonal components of myocardial motion (longitudinal, circumferential, and radial), and (b) rotation and torsion. Strain expresses the local myocardial deformation and is prone to important physiologic heterogeneities. Peak systolic strain is in the range of -15% to -20% for the longitudinal and circumferential components (fiber shortening) and 30%-40% for the radial component (wall thickening). The helical arrangement of myofibers that run in opposite directions at the epicardium and endocardium explains systolic twist (∼15°). This torsion may be enhanced during the early stage of several diseases (eg, hypertrophic cardiomyopathy) or in heart failure with a normal left ventricular ejection fraction. Strain is generally impaired in ischemic heart disease and cardiomyopathy, but the most diagnostically significant finding is the early identification of contractile dysfunction on the basis of longitudinal and circumferential strain reduction in patients with apparently preserved systolic function. Thus, strain impairment appears to be a sensitive and promising marker of subclinical disease, with the potential for improving patient management. © RSNA, 2012.
Mi-Young Jeung; Philippe Germain; Pierre Croisille; Soraya El Ghannudi; Catherine Roy; Afshin Gangi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiographics : a review publication of the Radiological Society of North America, Inc     Volume:  32     ISSN:  1527-1323     ISO Abbreviation:  Radiographics     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-09-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8302501     Medline TA:  Radiographics     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1381-98     Citation Subset:  IM    
Departments of Radiology B and Cardiology, University Hospital of Strasbourg, NHC, 1 Place de l'Hôpital, 67091 Strasbourg, France.
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