| Myocardial SPECT images for diagnosis of pulmonary hypertension and right ventricular hypertrophy. | |
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MedLine Citation:
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PMID: 21078778 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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METHODS: We identified 33 patients with normal findings on stress (99m)Tc-tetrofosmin left ventricular myocardial perfusion imaging who had a complete 2-dimensional echocardiographic study within 3 wk of the SPECT study. Two 6 × 6 pixel regions of interest were placed in the right and left ventricular free walls of both non-attenuation-corrected and attenuation-corrected SPECT images. We examined the correlation of RV/LV uptake ratio with echocardiographic right ventricular free-wall thickness and with pulmonary artery systolic pressure. RESULTS: RV/LV uptake ratio, measured on non-attenuation-corrected images, correlated significantly with both pulmonary artery systolic pressure (r = 0.63 and P < 0.001) and right ventricular wall thickness (r = 0.6 and P < 0.001). Receiver-operating-characteristic analysis of the use of RV/LV uptake ratio to detect significant pulmonary hypertension showed that the area under the curve was 0.78 (95% confidence interval, 0.62-0.95). However, no significant correlation of RV/LV uptake ratio with pulmonary artery systolic pressure or right ventricular wall thickness was found on attenuation-corrected images. CONCLUSION: RV/LV uptake ratio measured on SPECT images can be used to identify patients with high pulmonary artery pressure or right ventricular hypertrophy. |
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Authors:
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Reza M Mazraeshahi; Jeffrey Striet; Ryan C Oeltgen; Myron C Gerson |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-11-15 |
Journal Detail:
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Title: Journal of nuclear medicine technology Volume: 38 ISSN: 1535-5675 ISO Abbreviation: J Nucl Med Technol Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0430303 Medline TA: J Nucl Med Technol Country: United States |
Other Details:
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Languages: eng Pagination: 175-80 Citation Subset: IM |
Affiliation:
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Division of Cardiovascular Diseases, University of Cincinnati, Cincinnati, Ohio 45267-0542, USA. reza.mazraeshahi@uc.edu |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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