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Myocardial Infarction after Rituximab Treatment for Rheumatoid Arthritis: Is there a Link?
MedLine Citation:
PMID:  23565629     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Rituximab is a anti-CD20 monoclonal antibody often used in the treatment of rheumatoid arthritis (RA). Infusion reactions sometimes develop following rituximab administration. Delayed complications are rare. Acute coronary syndromes are listed as side-effects of rituximab therapy. We report two cases of acute myocardial infarction following rituximab therapy for RA and review the literature regarding cardiac events in patients treated with rituximab. We would like to raise awareness of this possible complication in patients treated with rituximab.
Authors:
Alper M van Sijl; Wilfred van der Weele; Michael T Nurmohamed
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-4-02
Journal Detail:
Title:  Current pharmaceutical design     Volume:  -     ISSN:  1873-4286     ISO Abbreviation:  Curr. Pharm. Des.     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-4-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9602487     Medline TA:  Curr Pharm Des     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Rheumatology, Jan van Breemen Research Institute, Reade P.O. Box 58271, 1040 HG, Amsterdam, The Netherlands. a.v.sijl@reade.nl; alper.vansijl@vumc.nl.
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