| Myeloid sarcoma involving the breast. | |
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MedLine Citation:
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PMID: 20698144 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Myeloid sarcoma is a tumor mass with extramedullary growth pattern, composed of myeloblasts or immature myeloid cells. The development of myeloid sarcoma may precede or concur with acute or chronic myeloid leukemia (AML or CML) or other myeloproliferative diseases or myelodysplastic syndromes (MDS). Isolated myeloid sarcoma of the breast is very rare. A case is presented of a 25-year-old, previously healthy woman that presented to our department for a palpable node, 5 x 2 cm in size, in the upper medial quadrant of her left breast. Fine needle aspiration (FNA) produced a sample consisting of medium sized blasts. Additional work-up revealed anemia, thrombocytopenia and leukocytosis, along with atypical blasts detected in peripheral blood and bone marrow smear. Based on the morphology, cytochemical characteristics and immature cell immunophenotype, it was considered a case of acute myeloid leukemia without maturation. In spite of intensive chemotherapy, the patient died within a year of diagnosis. In cases of isolated breast myeloid sarcoma, the diagnosis can be missed if the possibility of myeloid sarcoma is not remembered on differential diagnosis of a breast neoplasm. |
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Authors:
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Biljana Jelić-Puskarić; Slobodanka Ostojić-Kolonić; Ana Planinc-Peraica; Dragica Obad-Kovacević; Ika Kardum-Skelin; Branimir Jaksić |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Collegium antropologicum Volume: 34 ISSN: 0350-6134 ISO Abbreviation: Coll Antropol Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-08-11 Completed Date: 2010-09-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8003354 Medline TA: Coll Antropol Country: Croatia |
Other Details:
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Languages: eng Pagination: 641-4 Citation Subset: IM |
Affiliation:
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Department of Medicine, Laboratory for Cytology and Hematology, "Merkur" University Hospital, Zagreb, Croatia. biljana.jelic.puskaric@zg.t-com.hr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anemia / etiology, pathology Biopsy, Fine-Needle Bone Marrow / pathology Breast Neoplasms / pathology* Fatal Outcome Female Humans Leukemia, Myeloid, Acute / pathology Leukocytosis / etiology, pathology Recurrence Sarcoma, Myeloid / pathology* Thrombocytopenia / etiology, pathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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