Document Detail

Myelofibrosis in a cat (abstract).
MedLine Citation:
PMID:  16032299     Owner:  NLM     Status:  In-Data-Review    
A 2-year-old female domestic shorthair cat was presented with ill-health and marked ascites. Clinically, there was marked pallor of mucous membranes. Two haematological examinations and transudate-exudate analyses of peritoneal fluid were conducted 1 week apart, as well as a coagulation screen and routine serum biochemistry. The haematological examinations revealed a severe persistent non-regenerative anaemia. There were no abnormalities within the neutrophil and lymphocyte cell lines. Very occasional nucleated red blood cells (RBCs) in peripheral circulation and some RBC agglutination were seen. Analysis of peritoneal fluid disclosed a modified transudate, and small numbers of erythroid and myeloid precursors were observed on the second occasion. The cat was FIV/FeLV-negative, and there were no coagulation abnormalities. Following necropsy and histopathological examination, myelofibrosis and extramedullary haematopoiesis were seen. Thoracic masses were hyperplastic lymph nodes in which there was evidence of extramedullary haematopoiesis. The exact cause of the myelofibrosis was not obvious but it may have been a case of myeloid metaplasia, however not all the characteristics of this entity were present.
J C Thompson
Related Documents :
6236889 - Possible role of sialic acid and endogenous neuraminidase in t-cell proliferation.
3293309 - Preparation and characterization of monoclonal antibodies against bovine b lymphocyte s...
22728319 - Local transplant of human umbilical cord matrix stem cells improves skin flap survival ...
830419 - Differences in the responsiveness of splenic, lymph node, and peripheral blood lymphoid...
6951809 - Transfer, tissue localization and proliferation of fetal cells in pregnant mice.
562149 - The origin of iga-containing cells in intestinal lymph of sheep.
15361869 - Early b cell factor cooperates with runx1 and mediates epigenetic changes associated wi...
12544769 - Effects of amifostine on clonogenic mesenchymal progenitors and hematopoietic progenito...
12811849 - Naive and memory b cells respond differentially to t-dependent signaling but display an...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  New Zealand veterinary journal     Volume:  51     ISSN:  0048-0169     ISO Abbreviation:  N Z Vet J     Publication Date:  2003 Feb 
Date Detail:
Created Date:  2005-07-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0021406     Medline TA:  N Z Vet J     Country:  New Zealand    
Other Details:
Languages:  eng     Pagination:  46     Citation Subset:  -    
Gribbles Veterinary Pathology, PO Box 356, Palmerston North, New Zealand.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Bovine and ovine mycoplasmal arthritis and synovitis (abstract).
Next Document:  The use of genetic modification technologies in the discovery of genes affecting production traits a...