| Myelodysplastic syndromes: a practical approach to diagnosis and treatment. | |
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MedLine Citation:
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PMID: 20048028 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The myelodysplastic syndromes (MDS) are clonal bone marrow disorders that lead to underproduction of normal blood cells. The consequent cytopenias result in infections and bleeding complications. MDS transform to acute myeloid leukemia in one-third of patients. The number of diagnoses has exploded in the past decade as a result of increased recognition and understanding of the disease and the aging of the population. New therapies can extend life. MDS are now considered the most common form of leukemia, and in some cases deserve immediate intervention. This review describes common presentations of MDS, optimal diagnostic approaches, and therapies for lower-and higher-risk disease. |
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Authors:
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Afsaneh Barzi; Mikkael A Sekeres |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Cleveland Clinic journal of medicine Volume: 77 ISSN: 1939-2869 ISO Abbreviation: Cleve Clin J Med Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2010-01-05 Completed Date: 2010-03-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8703441 Medline TA: Cleve Clin J Med Country: United States |
Other Details:
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Languages: eng Pagination: 37-44 Citation Subset: IM |
Affiliation:
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Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH 44195, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Age Distribution Anemia / etiology Anti-Bacterial Agents / therapeutic use Blood Cell Count Chelation Therapy Erythrocyte Transfusion Erythropoietin, Recombinant / therapeutic use Hematinics / therapeutic use Humans Myelodysplastic Syndromes / classification, diagnosis*, etiology, therapy* |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/Erythropoietin, Recombinant; 0/Hematinics |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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