| Myelodysplastic syndrome with thrombocytosis in a patient with Klinefelter's syndrome. | |
| | |
MedLine Citation:
|
PMID: 8480486 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We report herein a patient with Klinefelter's syndrome associated with refractory anemia with excess of blasts in transformation, a subtype of myelodysplastic syndrome (MDS). The MDS developed with karyotypic abnormality involving t(4;7)(q21;q11), and was characteristic of marked thrombocytosis and marrow infiltration by many atypical megakaryocytes. The patient also had diabetes mellitus and a disturbed immune system. To our knowledge, this is the fifth reported case of MDS in patients with Klinefelter's syndrome in the literature. |
| | |
Authors:
|
K Yamauchi |
Related Documents
:
|
22570676 - Teduglutide, a novel glucagon-like peptide 2 analog, in the treatment of patients with ... 21192196 - Toxoplasmosis myelopathy and myopathy in an aids patient: a case of immune reconstituti... 20507306 - Malignancies and survival patterns in the national cancer institute inherited bone marr... 1613716 - A patient with werner's syndrome and osteosarcoma presenting as scleroderma. 20060116 - Large brachial artery diameter and metabolic syndrome in postmenopausal women. 22305256 - Establishing a web-based integrated surveillance system for early detection of infectio... |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Acta haematologica Volume: 89 ISSN: 0001-5792 ISO Abbreviation: Acta Haematol. Publication Date: 1993 |
Date Detail:
|
Created Date: 1993-05-21 Completed Date: 1993-05-21 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0141053 Medline TA: Acta Haematol Country: SWITZERLAND |
Other Details:
|
Languages: eng Pagination: 43-5 Citation Subset: IM |
Affiliation:
|
Department of Internal Medicine, Tokai University School of Medicine, Tokyo, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Anemia, Refractory, with Excess of Blasts
/
complications*,
genetics,
pathology Bone Marrow / pathology Chromosomes, Human, Pair 4 Chromosomes, Human, Pair 7 Humans Karyotyping Klinefelter Syndrome / complications* Male Megakaryocytes / pathology Middle Aged Thrombocytosis / complications*, genetics Translocation, Genetic |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Severe osteoporosis and multiple vertebral collapses in a child during treatment for B-ALL.
Next Document: B-type large-cell primary splenic lymphoma with massive involvement of the red pulp.