| Myelodysplastic syndrome with prolonged reticulocyte survival mimicking hemolytic disease. | |
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MedLine Citation:
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PMID: 8116568 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A patient with myelodysplastic syndrome (refractory anemia) with marked and persistent reticulocytosis is presented. A referring diagnosis of hemolytic disease had been made. However, the 51Cr red cell survival was normal (T1/2 24 days). Reticulocyte morphology, red cell creatine content, and in vitro reticulocyte survival studies have suggested that the reticulocytosis arose as a consequence of delayed maturation of the reticulocytes. Two patients with myelodysplastic syndrome and delayed reticulocyte maturation have previously been described; in both patients, however, red cell survival was also shortened. Anemia with reticulocytosis, mimicking hemolytic disease, may be an unusual presentation of myelodysplastic syndrome. |
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Authors:
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G D Sher; P H Pinkerton; M A Ali; J S Senn |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: American journal of clinical pathology Volume: 101 ISSN: 0002-9173 ISO Abbreviation: Am. J. Clin. Pathol. Publication Date: 1994 Feb |
Date Detail:
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Created Date: 1994-03-30 Completed Date: 1994-03-30 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370470 Medline TA: Am J Clin Pathol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 149-53 Citation Subset: AIM; IM |
Affiliation:
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Department of Laboratory Hematology, Sunnybrook Health Science Centre, Toronto, Ontario, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Anemia, Hemolytic / blood, diagnosis*, pathology Cell Differentiation / physiology Cell Survival / physiology Chromium Radioisotopes Creatinine / analysis Diagnosis, Differential Female Humans Myelodysplastic Syndromes / blood*, diagnosis*, pathology Reticulocytes / chemistry, pathology* |
| Chemical | |
Reg. No./Substance:
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0/Chromium Radioisotopes; 60-27-5/Creatinine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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