Document Detail


Myelodysplastic syndrome complicated by central diabetes insipidus and cerebral salt wasting syndrome with peculiar change in magnetic resonance images.
MedLine Citation:
PMID:  20075582     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Central diabetes insipidus (CDI) could occurs in patients with myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML), because of infiltration of leukemic cells into the neurohypophysis or some other reason and it is closely associated with abnormalities of chromosome 7. We report a case of MDS with abnormalities of chromosome 7, presenting as CDI followed by deterioration of polyuria and hyponatremia with a decreased extracellular fluid volume. Magnetic resonance imaging (MRI) revealed symmetrically enhanced lesions in the hypothalamus. Fludrocortisone treatment normalized his serum sodium level and cerebral salt wasting syndrome (CSWS) was suspected.
Authors:
Soichi Sano; Keiko Yamagami; Takashi Morikawa; Katsunobu Yoshioka
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-01-15
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  49     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2010  
Date Detail:
Created Date:  2010-01-15     Completed Date:  2010-08-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  161-5     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, Osaka City General Hospital, Osaka.
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MeSH Terms
Descriptor/Qualifier:
Aged
Brain Diseases, Metabolic / complications,  pathology*
Diabetes Insipidus, Neurogenic / complications,  pathology*
Humans
Hyponatremia / complications,  pathology*
Magnetic Resonance Imaging* / methods
Male
Myelodysplastic Syndromes / complications,  pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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