Document Detail

Myelodysplastic syndrome associated with erythrophagocytosis by blasts and myeloid cells.
MedLine Citation:
PMID:  8589370     Owner:  NLM     Status:  MEDLINE    
A 63-year-old man with refractory anemia with excess of blasts in transformation exhibited erythroid hyperplasia, dyserythropoiesis, a del(20q) abnormality, susceptibility to bacterial infections, and a relatively short survival. Phagocytosis of erythrocytes by blast cells was observed. Erythrophagocytosis was also seen in myeloid cells, including promyelocytes, myelocytes, metamyelocytes and neutrophils. Neither the monocytes nor the macrophages showed erythrophagocytosis. This is the first report of erythrophagocytosis by blasts and myeloid cells in a patient with myelodysplastic syndrome.
J Kuyama; M Fushino; H Take; Y Kanayama
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  International journal of hematology     Volume:  62     ISSN:  0925-5710     ISO Abbreviation:  Int. J. Hematol.     Publication Date:  1995 Dec 
Date Detail:
Created Date:  1996-03-27     Completed Date:  1996-03-27     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9111627     Medline TA:  Int J Hematol     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  243-6     Citation Subset:  IM    
Department of Internal Medicine, Toyonaka Municipal Hospital, Hyogo, Japan.
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MeSH Terms
Anemia, Refractory, with Excess of Blasts / blood,  physiopathology*
Erythropoiesis / physiology*
Hematopoietic Stem Cells / physiology*
Middle Aged
Phagocytosis / physiology*

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