Document Detail

Myelination of the optic radiation in Leber congenital amaurosis.
MedLine Citation:
PMID:  1443398     Owner:  NLM     Status:  MEDLINE    
We have studied the myelination of the visual pathway by magnetic resonance imaging in seven children (aged 5 months to 16 years) with Leber congenital amaurosis. The corpus geniculatum laterale and the retrogeniculate optic radiation had a normal appearance on MRI in all patients. Therefore we conclude that normal myelination of the optic radiation, as it can be grossly assessed by MRI, can take place even with absent or greatly reduced visual sensory input.
M Steinlin; E Martin; K Schenker; E Boltshauser
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Brain & development     Volume:  14     ISSN:  0387-7604     ISO Abbreviation:  Brain Dev.     Publication Date:  1992 Jul 
Date Detail:
Created Date:  1992-12-02     Completed Date:  1992-12-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7909235     Medline TA:  Brain Dev     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  212-5     Citation Subset:  IM    
Children's University Hospital, Zurich, Switzerland.
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MeSH Terms
Blindness / congenital*,  pathology,  physiopathology
Child, Preschool
Magnetic Resonance Imaging
Myelin Sheath / physiology*
Occipital Lobe / pathology
Optic Atrophies, Hereditary / pathology,  physiopathology*
Optic Nerve / physiopathology
Retinal Ganglion Cells / physiology

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