Document Detail

Myelination of the human fetal phrenic nerve.
MedLine Citation:
PMID:  7113635     Owner:  NLM     Status:  MEDLINE    
The formation of the myelin sheath of the human phrenic nerve has been studied by electron microscopy in fetuses aged 15, 17, and 23 postovulatory weeks. At 15 weeks, the phrenic nerve is composed mainly of large bundles of axons surrounded by lemmocyte processes. However, fibres at the beginning of myelination are present and show one or one and a half turns of lemmocyte process. At 17 weeks, an increasing number of myelinating fibers can be noted, and the formation of compact myelin and laminated perineurium is detectable. The phrenic nerve presents a mature form by 23 postovulatory weeks. At this time many axons have acquired a thick, compact myelin sheath. However, fibres at early stage of myelin formation are still visible.
W Woźniak; R O'Rahilly; M Bruska
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Acta anatomica     Volume:  112     ISSN:  0001-5180     ISO Abbreviation:  Acta Anat (Basel)     Publication Date:  1982  
Date Detail:
Created Date:  1982-10-21     Completed Date:  1982-10-21     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370272     Medline TA:  Acta Anat (Basel)     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  281-96     Citation Subset:  IM    
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MeSH Terms
Fetus / anatomy & histology
Microscopy, Electron
Myelin Sheath / physiology*,  ultrastructure
Phrenic Nerve / embryology*,  ultrastructure
Grant Support

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