| Myelinated retinal nerve fibers. | |
| | |
MedLine Citation:
|
PMID: 7234927 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
In a series of 3,968 consecutive autopsies, myelinated nerve fibers of the retina were presented in 39 (0.98%) cases and bilateral in three (7.7%) affected cases; thus, 42 (0.54%) of the 7,936 eyes examined were affected. Myelinated nerve fiber lesions appeared as white or gray-white striated patches corresponding in shape to the distribution of retinal nerve fibers and demonstrated frayed borders. Myelinated retinal nerve fibers were continuous with the optic nerve head in 14 (33%) and discontinuous with the optic nerve head in 28 (66%) affected eyes. By light microscopy and electron microscopy, myelinated retinal fibers were marked by a ganglion cell axon surrounded by concentric lipoprotein lamellae that formed the myelin sheath. Glial cells were often prominent near the myelin sheaths, but other components of the sensory retina were morphologically normal. Clinically, 32 patients with myelinated retinal nerve fibers had comparable overall features, visual field defects less extensive than expected on the basis of ophthalmoscopic appearance, and normal findings on fluorescein angiography. Four patients had a syndrome characterized by ipsilateral extensive myelinated retinal nerve fibers, anisometropic myopia, amblyopia, and strabismus. |
| | |
Authors:
|
B R Straatsma; R Y Foos; J R Heckenlively; G N Taylor |
Related Documents
:
|
1618287 - A morphological and morphometric analysis of the optic nerve in the hypothyroid rat. 23748997 - Increased sarcolipin expression and decreased sarco(endo)plasmic reticulum ca(2+) uptak... 7160537 - Selective effects of myo-inositol administration on sciatic and tibial motor nerve cond... 10679687 - Neural and connective tissue response to long-term implantation of multiple contact ner... 12115927 - Ubiquitin and actin expression in claw muscles of land crab, gecarcinus lateralis, and ... 2454437 - Protective action of ruthenium red toward capsaicin desensitization of sensory fibers. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: American journal of ophthalmology Volume: 91 ISSN: 0002-9394 ISO Abbreviation: Am. J. Ophthalmol. Publication Date: 1981 Jan |
Date Detail:
|
Created Date: 1981-07-23 Completed Date: 1981-07-23 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0370500 Medline TA: Am J Ophthalmol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 25-38 Citation Subset: AIM; IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Aged Child Child, Preschool Female Fluorescein Angiography Fundus Oculi Humans Infant Middle Aged Nerve Fibers, Myelinated / cytology* Ophthalmoscopy Optic Nerve / cytology Retina / cytology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Ocular torsion and primary retinal meridians.
Next Document: The origins of Sattler's veil.