| Mycotoxins: food contamination, mechanism, carcinogenic potential and preventive measures. | |
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MedLine Citation:
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PMID: 2017214 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Mycotoxins constitute a large number of naturally occurring fungal secondary metabolites with very diversified toxic effects in humans and animals. Among many mycotoxins discovered, aflatoxins, ochratoxin A, sterigmatocystin and several others are identified as carcinogens; several others were found to be mutagenic. Nevertheless, aflatoxin B1 has been found to be one of the most potent carcinogens and contamination of aflatoxins in the food supply is still a major concern. Whereas extensive studies have been made on aflatoxins, little is known about the mode of action of other carcinogenic and mutagenic mycotoxins. Recent progress on research for the carcinogenic and mutagenic mycotoxins is presented in this review with emphasis on their contamination in foods, their carcinogenic potential to humans, and the mode of action as well as possible preventive measures. |
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Authors:
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F S Chu |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
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Title: Mutation research Volume: 259 ISSN: 0027-5107 ISO Abbreviation: Mutat. Res. Publication Date: 1991 Mar-Apr |
Date Detail:
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Created Date: 1991-05-21 Completed Date: 1991-05-21 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0400763 Medline TA: Mutat Res Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 291-306 Citation Subset: IM |
Affiliation:
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Food Research Institute, University of Wisconsin-Madison 53706. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aflatoxins
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toxicity Animals Carcinogens Food Contamination* Humans Mutagens Mycotoxins / analysis, toxicity* Ochratoxins / toxicity Sterigmatocystin / toxicity |
| Grant Support | |
ID/Acronym/Agency:
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CA 15064/CA/NCI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Aflatoxins; 0/Carcinogens; 0/Mutagens; 0/Mycotoxins; 0/Ochratoxins; 10048-13-2/Sterigmatocystin; 303-47-9/ochratoxin A |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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