Document Detail

Mycotoxin food and feed regulation and the specific case of ochratoxin A: a review of the worldwide status.
MedLine Citation:
PMID:  20658402     Owner:  NLM     Status:  MEDLINE    
Mycotoxins are naturally occurring contaminants whose presence in food- and feedstuffs cannot be completely avoided. The safety and economic impact arising from the commercialization of mycotoxin-contaminated food and feed supply chain is considerable and acknowledged. To protect consumers from mycotoxin-derived health risks, many countries have adopted regulations or guidelines to limit exposure. Similar to regulation for other mycotoxins, the regulatory status of ochratoxin A (OTA) lacks consensus. Although this was one of the first fungal toxins to be subjected to compliance control due to its toxic properties, the conflict between the prime objective of consumer health safeguard and the economic interests of producers and traders remains. One of the key challenges facing policymakers is to balance these conflicting demands and reach consensual regulatory actions or limits. The noteworthy transboundary implications are recognized, both in the case of absence as the unsubstantiated tightening of regulatory limits. This paper scrutinizes the rationales and implications of mycotoxin regulation, with special attention devoted to OTA. In view of the ongoing debate concerning this complex issue, a review of the arguments and suggested strategies proposed by different parties is also made. The specific case of OTA regulation in food and feed is updated and analysed at a European Union and global level.
S C Duarte; C M Lino; A Pena
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment     Volume:  27     ISSN:  1944-0057     ISO Abbreviation:  Food Addit Contam Part A Chem Anal Control Expo Risk Assess     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-08-23     Completed Date:  2010-12-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101485040     Medline TA:  Food Addit Contam Part A Chem Anal Control Expo Risk Assess     Country:  England    
Other Details:
Languages:  eng     Pagination:  1440-50     Citation Subset:  IM    
Group of Health Surveillance, Center of Pharmaceutical Studies, University of Coimbra, Polo III, Azinhaga de Sta Comba, P-3000-548 Coimbra, Portugal.
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MeSH Terms
Animal Feed / analysis*
Beverages / analysis
Carcinogens / analysis
Cereals / chemistry
European Union
Food Analysis / methods
Food Contamination / analysis*,  legislation & jurisprudence*
Maximum Allowable Concentration
Mycotoxins / analysis*
Ochratoxins / analysis*
Quality Control
Risk Assessment
Reg. No./Substance:
0/Carcinogens; 0/Mycotoxins; 0/Ochratoxins; 303-47-9/ochratoxin A

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