Document Detail

Mycotic pseudoaneurysm of the left circumflex coronary artery: a fatal complication following drug-eluting stent implantation.
MedLine Citation:
PMID:  17238176     Owner:  NLM     Status:  MEDLINE    
Coronary artery stent infection is a rare complication of percutaneous intervention. We report a case of fulminant coronary stent infection with Staphylococcus aureus presenting as a pseudoaneurysm of the left circumflex artery following repeated implantation of drug-eluting stents in the setting of multiple episodes of recurrent in-stent restenosis. We speculate that sirolimus- and paclitaxel-eluting stents may be more likely to predispose to infection than bare metal stents because of their immunomodulating and antiproliferative effects.
Mimi Q Le; Craig R Narins
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions     Volume:  69     ISSN:  1522-1946     ISO Abbreviation:  Catheter Cardiovasc Interv     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-03-01     Completed Date:  2007-07-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100884139     Medline TA:  Catheter Cardiovasc Interv     Country:  United States    
Other Details:
Languages:  eng     Pagination:  508-12     Citation Subset:  IM    
Copyright Information:
(c) 2006 Wiley-Liss, Inc.
Division of Cardiology, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA.
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MeSH Terms
Aneurysm, False / etiology*,  microbiology
Aneurysm, Infected / etiology*,  microbiology
Blood Vessel Prosthesis Implantation / adverse effects
Cardiovascular Agents / adverse effects
Cell Proliferation / drug effects
Coronary Restenosis / surgery*
Fatal Outcome
Immunosuppressive Agents / adverse effects
Paclitaxel / adverse effects
Prosthesis-Related Infections / etiology
Sirolimus / adverse effects
Staphylococcal Infections / etiology*
Staphylococcus aureus
Stents / adverse effects*
Reg. No./Substance:
0/Cardiovascular Agents; 0/Immunosuppressive Agents; 33069-62-4/Paclitaxel; 53123-88-9/Sirolimus

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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