Document Detail

Mycotic aneurysm of the descending thoracic aorta caused by Pseudomonas aeruginosa in a solid organ transplant recipient: case report and review.
MedLine Citation:
PMID:  12593697     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Pseudomonas aeruginosa is a rare cause of aortic mycotic aneurysms. Optimal treatment, including reconstructive graft material and appropriate length of antibiotic therapy, is being debated. METHODS: We describe a 26-year-old kidney-pancreas recipient who developed an aneurysm of the descending thoracic aorta caused by P. aeruginosa. RESULTS: After surgical debridement and cryopreserved allograft reconstruction, parenteral antibiotics were continued for 12 months, at which time the patient was converted to oral antibiotic therapy. Within 6 months, he redeveloped a thoracic aortic aneurysm, necessitating reoperation and lifelong parenteral antibiotic therapy. CONCLUSION: Herein we review and discuss the relevant literature concerning surgical and antibiotic treatment of mycotic thoracic aneurysms.
Brad A Feltis; David A Lee; Gregory J Beilman
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Surgical infections     Volume:  3     ISSN:  1096-2964     ISO Abbreviation:  Surg Infect (Larchmt)     Publication Date:  2002  
Date Detail:
Created Date:  2003-02-20     Completed Date:  2003-04-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9815642     Medline TA:  Surg Infect (Larchmt)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  29-33     Citation Subset:  IM    
Department of Surgery, University of Minnesota, Mayo Mail Code 195, 420 Delaware Street SE, Minneapolis, MN 55455, USA.
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MeSH Terms
Aneurysm, Infected / therapy*
Aortic Aneurysm, Thoracic / therapy*
Aztreonam / administration & dosage*
Blood Vessel Prosthesis Implantation
Drug Therapy, Combination / administration & dosage*
Infusions, Parenteral / methods
Organ Transplantation*
Penicillanic Acid / administration & dosage*,  analogs & derivatives
Piperacillin / administration & dosage*
Pseudomonas Infections / therapy*
Recurrence / prevention & control
Treatment Outcome
Vancomycin / administration & dosage*
Reg. No./Substance:
1404-90-6/Vancomycin; 157044-21-8/piperacillin-tazobactam combination product; 61477-96-1/Piperacillin; 78110-38-0/Aztreonam; 87-53-6/Penicillanic Acid

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