Document Detail

Mycoplasma meningitis in infants with spina bifida.
MedLine Citation:
PMID:  1107109     Owner:  NLM     Status:  MEDLINE    
Infants with myelomeningocele are liable to develop bacterial colonisation of the lesion which, in the case of Gram-negative bacteria, often progresses to meningitis because of the infants' immature immune status. The time and origin of the bacterial colonisation usually are uncertain. This study reports seven cases of meningitis caused by Mycoplasma hominis, an organism not previously reported to cause meningitis. The commensal status of Mycoplasma hominis in the vagina of many women, and its isolation from the mother of one patient in this group, suggests that the infant acquired the organism in the birth canal and that infection developed over a period of days. Routine cultures from the sac or wound did not show the presence of organisms until after the child had developed signs and symptoms of meningitis. Commensal organisms from the vagina may lie dormant for several days within the closed myelomeningocele and their more virulent strains may then produce meningitis. It is suggested that neonatal meningitis may be caused by organisms acquired during birth, as well as by those to which the infant is exposed later.
S R Wealthall
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Developmental medicine and child neurology. Supplement     Volume:  -     ISSN:  0419-0238     ISO Abbreviation:  Dev Med Child Neurol Suppl     Publication Date:  1975  
Date Detail:
Created Date:  1976-03-18     Completed Date:  1976-03-18     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0006762     Medline TA:  Dev Med Child Neurol Suppl     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  117-22     Citation Subset:  IM    
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MeSH Terms
Infant, Newborn
Infant, Newborn, Diseases*
Meningitis / cerebrospinal fluid,  complications*
Mycoplasma / isolation & purification
Mycoplasma Infections / complications*,  mortality,  transmission
Spinal Dysraphism / cerebrospinal fluid,  complications*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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