| Mycoplanecins, novel antimycobacterial antibiotics from Actinoplanes awajinensis subsp. mycoplanecinus subsp. nov. III. Structural determination of mycoplanecin A. | |
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MedLine Citation:
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PMID: 6630067 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The structure of mycoplanecin A was determined by the analysis of chemical degradation products and by mass and 1H and 13C NMR spectrometries. Mycoplanecin A is a new cyclic peptide antibiotic composed of mol each of alpha-ketobutyric acid, glycine, L-leucine, L-proline, L-2-amino-5-methylhexanoic acid, N-methyl-D-leucine, N-methyl-L-threonine, methyl-L-proline and ethyl-L-proline and two mol of N-methyl-L-valine. Among these components, ethyl-L-proline is reported for the first time as a component of natural products. A newly developed mass analysis has been introduced for the differentiation of alpha-amino acid and its N-methyl derivative. |
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Authors:
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M Nakajima; A Torikata; H Tamaoki; T Haneishi; M Arai; T Kinoshita; H Kuwano |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of antibiotics Volume: 36 ISSN: 0021-8820 ISO Abbreviation: J. Antibiot. Publication Date: 1983 Aug |
Date Detail:
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Created Date: 1983-12-17 Completed Date: 1983-12-17 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0151115 Medline TA: J Antibiot (Tokyo) Country: JAPAN |
Other Details:
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Languages: eng Pagination: 967-75 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Actinomycetales
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growth & development* Amino Acid Sequence Anti-Bacterial Agents* Hydrolysis Indicators and Reagents Magnetic Resonance Spectroscopy Mass Spectrometry Peptides / isolation & purification Protein Conformation |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/Indicators and Reagents; 0/Peptides; 72993-51-2/mycoplanecin A |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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