Document Detail

Mycobacterium xenopi infection of the spine: a case report and literature review.
MedLine Citation:
PMID:  10749641     Owner:  NLM     Status:  MEDLINE    
STUDY DESIGN: A case report of Mycobacterium xenopi. OBJECTIVES: To present a case report of a vertebral osteomyelitis caused by M. xenopi and to review the world literature on the subject. SUMMARY OF BACKGROUND DATA: M. xenopi is most commonly a pulmonary pathogen in immunosuppressed patients or those with underlying lung disease. Infection of the spine is very rare, with only four cases reported. Three of these cases occurred in immunosuppressed patients, and the fourth in a patient with previous tuberculosis osteomyelitis of the spine. METHODS: The information was obtained from a review of the patient's clinical notes and follow-up appointments. RESULTS: The patient was a 73-year-old woman with an M. xenopi osteomyelitis of T6-T7, confirmed by magnetic resonance imaging and a computed tomography-guided biopsy. She was treated with surgical decompression and stabilization before a 2-year antibiotic regimen was begun. At follow-up assessment 1 year after the antibiotics were finished, she still had some ongoing back pain, but no evidence of relapse. CONCLUSIONS: This is the first reported case of an M. xenopi infection of the spine in a patient with no predisposing factors. This type of infection can be difficult to treat, with a high relapse rate reported despite prolonged courses of antibiotics.
T Danesh-Clough; J C Theis; A van der Linden
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Spine     Volume:  25     ISSN:  0362-2436     ISO Abbreviation:  Spine     Publication Date:  2000 Mar 
Date Detail:
Created Date:  2000-07-21     Completed Date:  2000-07-21     Revised Date:  2009-07-09    
Medline Journal Info:
Nlm Unique ID:  7610646     Medline TA:  Spine (Phila Pa 1976)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  626-8     Citation Subset:  IM    
Departments of Orthopaedics and Microbiology, Dunedin Hospital, Dunedin, New Zealand.
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MeSH Terms
Mycobacterium xenopi*
Spinal Cord Compression / microbiology*,  radiography,  surgery
Spinal Fusion
Tuberculosis, Spinal / diagnosis*,  radiography,  surgery

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