Document Detail

Mycobacterium fortuitum complex endocarditis-case report and literature review.
MedLine Citation:
PMID:  11952729     Owner:  NLM     Status:  MEDLINE    
Endocarditis due to Mycobacterium fortuitum complex is a rare entity generally linked to the hospital environment. Only 18 cases have been published since 1966. Here we present a case of a female who developed an endocarditis due to Mycobacterium chelonae after valve replacement as well as a review of the literature. The course of this kind of endocarditis is generally subacute and the outcome is usually fatal. Blood cultures were positive in 75% of cases of metallic valve endocarditis, versus 20% in bioprostheses. The treatment must include antibiotics that have shown activity against these mycobacteria, such as amikacin, imipenem, cefoxitin, fluorinated quinolones and macrolides (especially clarithromycin). Surgical removal is recommended. Although the prognosis for the patient is poor, we should expect better outcomes with the use of new antibiotic regimens.
J Olalla; M Pombo; J M Aguado; E Rodríguez; E Palenque; J R Costa; E Riopérez
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases     Volume:  8     ISSN:  1198-743X     ISO Abbreviation:  Clin. Microbiol. Infect.     Publication Date:  2002 Feb 
Date Detail:
Created Date:  2002-04-15     Completed Date:  2002-05-29     Revised Date:  2006-11-07    
Medline Journal Info:
Nlm Unique ID:  9516420     Medline TA:  Clin Microbiol Infect     Country:  France    
Other Details:
Languages:  eng     Pagination:  125-9     Citation Subset:  IM    
Servicio de Medicina Interna, Hospital Universitario Doce de Octubre, Madrid, Spain.
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MeSH Terms
Aortic Valve Insufficiency / complications,  therapy
Endocarditis, Bacterial* / complications,  drug therapy,  etiology,  microbiology
Heart Valve Prosthesis / microbiology
Middle Aged
Mitral Valve Insufficiency / complications,  therapy
Mycobacterium Infections, Atypical* / complications,  drug therapy,  etiology,  microbiology
Mycobacterium fortuitum* / isolation & purification,  physiology

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