Document Detail


Mycobacterium abscessus pneumonia in an Atlantic bottlenose dolphin (Tursiops truncatus).
MedLine Citation:
PMID:  23272373     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Mycobacterium abscessus pneumonia was diagnosed antemortem in a 23-yr-old male Atlantic bottlenose dolphin (Tursiops truncatus). Clinical signs included lethargy, hyporexia, coughing, and bloody respiratory discharge. Diagnostic findings included neutrophilic leukocytosis, anemia, elevated erythrocyte sedimentation rate, and repeated forceful exhaled breath (sputum) cytology, with acute inflammatory cells and acid-fast positive beaded rods. The bacteria were initially identified free in the sputum sample and subsequently were seen within neutrophils. A culture was positive for a rapidly growing, white, colony-forming organism confirmed as M. abscessus by polymerase chain reaction and DNA sequencing. Clinical signs initially resolved with multidrug therapy. Concurrent Pseudomonas aeruginosa infection complicated clinical management and contributed to terminal decline. The dolphin was euthanized 5 mo after initial diagnosis. Necropsy results demonstrated acid-fast positive bacteria in lung tissue and supported the diagnosis of M. abscessus pneumonia. Acid-fast stains and mycobacteria cultures should be considered when evaluating ill dolphins.
Authors:
Leigh Ann Clayton; M Andrew Stamper; Brent R Whitaker; Catherine A Hadfield; Brian Simons; Joseph L Mankowski
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians     Volume:  43     ISSN:  1042-7260     ISO Abbreviation:  J. Zoo Wildl. Med.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-31     Completed Date:  2013-02-07     Revised Date:  2013-10-29    
Medline Journal Info:
Nlm Unique ID:  8915208     Medline TA:  J Zoo Wildl Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  961-5     Citation Subset:  IM    
Affiliation:
National Aquarium, Baltimore, MD 21202, USA. lclayton@aqua.org
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MeSH Terms
Descriptor/Qualifier:
Animals
Bottle-Nosed Dolphin*
Male
Mycobacterium / classification*,  isolation & purification*
Mycobacterium Infections / microbiology,  pathology,  veterinary*
Pneumonia, Bacterial / microbiology,  pathology,  veterinary*
Grant Support
ID/Acronym/Agency:
T32 RR007002/RR/NCRR NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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