Document Detail


Myasthenic crisis. Response to plasmapheresis following failure of intravenous gamma-globulin.
MedLine Citation:
PMID:  8352670     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Myasthenic crisis is a potentially life-threatening complication of myasthenia gravis that requires aggressive therapy. We describe four patients in whom myasthenic crisis developed and who failed to respond to initial treatment with intravenous gamma-globulin. All four patients subsequently responded to intensive plasma exchange. Based on our experience, plasmapheresis appears to be superior to intravenous gamma-globulin for the treatment of myasthenic crisis in certain patients. Prognostic factors that determine the effectiveness of intravenous gamma-globulin vs plasmapheresis in these patients merit further investigation.
Authors:
R B Stricker; B J Kwiatkowska; J A Habis; D D Kiprov
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of neurology     Volume:  50     ISSN:  0003-9942     ISO Abbreviation:  Arch. Neurol.     Publication Date:  1993 Aug 
Date Detail:
Created Date:  1993-09-15     Completed Date:  1993-09-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372436     Medline TA:  Arch Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  837-40     Citation Subset:  AIM; IM    
Affiliation:
Department of Medicine, California Pacific Medical Center, San Francisco, 94120.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Autoantibodies / blood
Female
Humans
Immunoglobulins, Intravenous
Male
Middle Aged
Myasthenia Gravis / immunology,  therapy*
Plasmapheresis*
Receptors, Cholinergic / immunology
Chemical
Reg. No./Substance:
0/Autoantibodies; 0/Immunoglobulins, Intravenous; 0/Receptors, Cholinergic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Factors that predict antiphospholipid immunoreactivity in young people with transient focal neurolog...
Next Document:  Brain magnetic resonance imaging in acute optic neuritis. Experience of the Optic Neuritis Study Gro...