Document Detail


Myasthenia gravis with thymoma: analysis of and postoperative prognosis for 65 patients with thymomatous myasthenia gravis.
MedLine Citation:
PMID:  6732348     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sixty-five patients with thymomatous myasthenia gravis were investigated. Thymomas were present in 44% of the male patients and 19% of the female patients with myasthenia gravis. The incidence of thymomatous disease in male patients was higher than in female patients in all age groups. Eighty percent of men more than 50 years old and women more than 60 years old had myasthenia gravis with thymoma. Germinal center formation in the thymus of patients with thymomatous myasthenia gravis was positive in 91% and was high grade. The prognosis for patients undergoing extended thymectomy of thymomatous myasthenia gravis was significantly better than in those having transsternal simple thymectomy, but it was worse than the prognosis for patients with nonthymomatous myasthenia gravis. No increase in the rate of remission or palliation was seen one year after thymectomy. It is concluded that early thymectomy is effective in control of myasthenia gravis in thymomatous myasthenia gravis.
Authors:
Y Monden; K Nakahara; K Kagotani; Y Fujii; A Masaoka; Y Kawashima
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  38     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  1984 Jul 
Date Detail:
Created Date:  1984-07-26     Completed Date:  1984-07-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  46-52     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Factors
Female
Humans
Male
Middle Aged
Myasthenia Gravis / complications*,  therapy
Prognosis
Sex Factors
Thymectomy / methods
Thymoma / complications*,  surgery
Thymus Neoplasms / complications*,  surgery
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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