Document Detail

Myasthenia gravis: two case reports and review of the literature.
MedLine Citation:
PMID:  22063376     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND OBJECTIVES: Myasthenia gravis (MG) is an autoimmune neurologic disease that affects the postsynaptic portion of the neuromuscular junction. It represents a challenge for anesthesiologists due to the diversity of disease manifestations and possibility of postoperative respiratory complications. The objective of this study was to demonstrate the importance of adequate monitoring of the neuromuscular blockade (NMB) due to the multiple presentations of MG.
CONTENTS: In this paper we report two cases of patients with MG. The first patient presented with the classical sensitivity to the neuromuscular blocker (NMB) and the second had a similar response to that of a normal patient. The literature review will be restricted to disease characteristics, while the description of its pathophysiology will focus on its reactions to NMB.
CONCLUSIONS: We suggest that, due to the multiple presentation and treatment of MG, neuromuscular transmission monitors are fundamental when using NMB.
Ana Laura Colle Kauling; Maria Cristina Simões de Almeida; Giovani de Figueiredo Locks; Guilherme Muriano Brunharo
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Revista brasileira de anestesiologia     Volume:  61     ISSN:  1806-907X     ISO Abbreviation:  Rev Bras Anestesiol     Publication Date:    2011 Nov-Dec
Date Detail:
Created Date:  2011-11-08     Completed Date:  2012-03-27     Revised Date:  2014-02-05    
Medline Journal Info:
Nlm Unique ID:  0401316     Medline TA:  Rev Bras Anestesiol     Country:  Brazil    
Other Details:
Languages:  eng; mul     Pagination:  748-63     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Editora Ltda. All rights reserved.
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MeSH Terms
Middle Aged
Monitoring, Intraoperative*
Myasthenia Gravis*
Neuromuscular Blockade*
Neuromuscular Blocking Agents / administration & dosage*
Reg. No./Substance:
0/Neuromuscular Blocking Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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