| Myasthenia gravis associated with penicillamine treatment for rheumatoid arthritis. | |
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MedLine Citation:
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PMID: 1125624 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Four patients with rheumatoid arthritis (R.A.) developed myasthenia gravis after taking penicillamine. In one patient withdrawal of the drug was followed by spontaneous remission of the myasthenia, and in two the dose of anticholinesterase was subsequently reduced. In the fourth patient continuing penicillamine treatment was associated with increasingly severe myasthenic features, but on withdrawal of the drug these resolved. As myasthenia gravis rarely complicates R.A. its onset in these patients shortly after the start of penicillamine treatment suggested that penicillamine may have precipitated this condition. |
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Authors:
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R C Bucknall; J Dixon A St; E N Glick; J Woodland; D W Zutshi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: British medical journal Volume: 1 ISSN: 0007-1447 ISO Abbreviation: Br Med J Publication Date: 1975 Mar |
Date Detail:
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Created Date: 1975-07-14 Completed Date: 1975-07-14 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0372673 Medline TA: Br Med J Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 600-2 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Arthritis, Rheumatoid / complications, drug therapy Cholinesterase Inhibitors / therapeutic use Female Humans Male Middle Aged Myasthenia Gravis / chemically induced*, complications, drug therapy Penicillamine / adverse effects*, therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Cholinesterase Inhibitors; 52-67-5/Penicillamine |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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