Document Detail


Myasthenia gravis. Diagnostic methods and control measures for a chronic disease.
MedLine Citation:
PMID:  8415329     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Myasthenia gravis should be entertained as a possible diagnosis in any patient who presents with muscle weakness or visual disturbance. The most common symptom is exacerbation of muscle fatigue with repeated use of the muscle and improvement with rest. Several inexpensive diagnostic tests for myasthenia gravis that can be performed by primary care physicians are available. Standard therapy in most cases is early thymectomy, followed by a highly individualized medication program that usually includes the anticholinesterase drug pyridostigmine bromide (Mestinon, Regonol). Corticosteroids and other immunosuppressive agents (usually azathioprine [Imuran]) may be added or substituted if response to anticholinesterase therapy is inadequate. Although myasthenia gravis is a chronic disease, it can be well controlled in most patients, provided they comply with treatment. Patient education is therefore essential.
Authors:
M S Juhn
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Postgraduate medicine     Volume:  94     ISSN:  0032-5481     ISO Abbreviation:  Postgrad Med     Publication Date:  1993 Oct 
Date Detail:
Created Date:  1993-11-03     Completed Date:  1993-11-03     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0401147     Medline TA:  Postgrad Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  161-4, 167-71, 174     Citation Subset:  AIM; IM    
Affiliation:
Garden City Hospital, Michigan.
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MeSH Terms
Descriptor/Qualifier:
Diagnosis, Differential
Female
Humans
Myasthenia Gravis / diagnosis*,  therapy*
Pregnancy
Pregnancy Complications / diagnosis,  therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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