| My dog's cheeks: A PBL project on collagen for cell biology and genetics courses. | |
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MedLine Citation:
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PMID: 21567871 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Students often have an oversimplified view of biological facts, which may hinder subsequent understanding when conceptual complexity gives rise to cognitive conflicts. To avoid this situation here, we present a PBL approach for the analysis of Ehlers-Danlos syndrome (EDS), which integrates a variety of topics in cell biology, genetics, and molecular biology, and it is used to illustrate the inherent complexities in some classical biological concepts. Students of two different courses analyze phenotypic, cellular, and molecular characteristics of EDS. Effect of mutations on collagen synthesis on collagen genes' expression and regulation or on connective tissues is reviewed and discussed. Information retrieval is used to develop students' skills in web-based molecular biology tools. Student interest and motivation is increased with the development of diagnostic protocols for a tissue biopsy and for an EDS causing mutation. Expected learning outcomes after completion of the project are also presented. Biochemistry and Molecular Biology Education Vol. 38, No. 6, pp. 410-415, 2010. |
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Authors:
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Alberto Vicario Casla; Isabel Smith Zubiaga |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology Volume: 38 ISSN: 1539-3429 ISO Abbreviation: Biochem Mol Biol Educ Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2011-05-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100970605 Medline TA: Biochem Mol Biol Educ Country: United States |
Other Details:
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Languages: eng Pagination: 410-5 Citation Subset: - |
Copyright Information:
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Copyright © 2010 International Union of Biochemistry and Molecular Biology, Inc. |
Affiliation:
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Dpto. de Genética, Antropología Física y Fisiología Animal. alberto.vicario@ehu.es. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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