| Mutilating palmoplantar keratoderma successfully treated with etretinate. | |
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MedLine Citation:
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PMID: 6084939 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Three patients, a mother and her two sons, with mutilating palmoplantar keratoderma (Vohwinkel's syndrome) were successfully treated with oral etretinate (Tigason). All of them had keratotic constriction furrows of one or more digits (pseudo-ainhum) with threatening spontaneous amputation. Oral treatment with etretinate brought about disappearance of the pseudo-ainhums and normalization of the digital blood circulation. The hyperkeratotic skin became thinned and pliable with a dose-dependent trend towards redness and atrophy. Continued long term etretinate medication has made it possible for these patients to fulfill their social and occupational activities. All 3 patients had acoustic impairment of high-pitched tone perception. |
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Authors:
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K Wereide |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta dermato-venereologica Volume: 64 ISSN: 0001-5555 ISO Abbreviation: Acta Derm. Venereol. Publication Date: 1984 |
Date Detail:
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Created Date: 1985-04-10 Completed Date: 1985-04-10 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370310 Medline TA: Acta Derm Venereol Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 566-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Etretinate / therapeutic use* Female Fingers / pathology Hearing Loss, High-Frequency / etiology Humans Keratoderma, Palmoplantar / drug therapy, genetics*, pathology Male Middle Aged Skin / pathology |
| Chemical | |
Reg. No./Substance:
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54350-48-0/Etretinate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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