| Mutation analysis of the C1QTNF3 gene in patients with schizophrenia. | |
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MedLine Citation:
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PMID: 20483475 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We previously identified a small region on chromosome 5p13 related to schizophrenia in a Puerto Rican pedigree. We screened one of the positional candidate genes, C1QTNF3, for mutations in affected family members. The direct sequencing identified 10 sequence variants, including five shared by all affected family members. Genotyping of the shared variants in a Puerto Rican sample of 118 cases and 136 controls did not reveal either allelic or genotype association with schizophrenia. |
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Authors:
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Irina Bespalova; Gary Angelo; Benjamin Ritter; Enrique Rossy-Fullana; Jose Carrion-Baralt; Martina Durner; Jeremy Silverman |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't Date: 2010-05-18 |
Journal Detail:
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Title: Psychiatry research Volume: 179 ISSN: 0165-1781 ISO Abbreviation: Psychiatry Res Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-09-03 Completed Date: 2010-10-26 Revised Date: 2012-05-07 |
Medline Journal Info:
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Nlm Unique ID: 7911385 Medline TA: Psychiatry Res Country: Ireland |
Other Details:
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Languages: eng Pagination: 235-7 Citation Subset: IM |
Copyright Information:
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Copyright © 2009 Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA. irina.bespalova@mssn.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Case-Control Studies DNA Mutational Analysis / methods Family Health Female Gene Frequency Genotype Hispanic Americans Humans Male Mutation / genetics* Schizophrenia / genetics* Tumor Necrosis Factors / genetics* |
| Grant Support | |
ID/Acronym/Agency:
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R03 MH082134-02/MH/NIMH NIH HHS; R03MH082134-01/MH/NIMH NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/C1QTNF3 protein, human; 0/Tumor Necrosis Factors |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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