Document Detail


Mutagens from the cooking of food. III. Survey by Ames/Salmonella test of mutagen formation in secondary sources of cooked dietary protein.
MedLine Citation:
PMID:  6751954     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A survey of mutagen formation during the cooking of a variety of protein-rich foods that are minor sources of protein intake in the American diet is reported (see Bjeldanes, Morris, Felton et al. (1982) for survey of major protein foods). Milk, cheese, tofu and organ meats showed negligible mutagen formation except following high-temperature cooking for long periods of time. Even under the most extreme conditions, tofu, cheese and milk exhibited fewer than 500 Ames/Salmonella typhimurium revertants/100 g equivalents (wet weight of uncooked food), and organ meats only double that amount. Beans showed low mutagen formation after boiling and boiling followed by frying (with and without oil). Only boiling of beans followed by baking for 1 hr gave appreciable mutagenicity (3650 revertants/100g equivalents). Seafood samples gave a variety of results: red snapper, salmon, trout, halibut and rock cod all gave more than 1000 revertants/100 g wet weight equivalents when pan-fried or griddle-fried for about 6 min/side. Baked or poached rock and deep-fried shrimp showed no significant mutagen formation. Broiled lamb chops showed mutagen formation similar to that in red meats tested in the preceding paper: 16,000 revertants/100 g equivalents. These findings show that as measured by bioassay in S. typhimurium, most of the foods that are minor sources of protein in the American diet are also minor sources of cooking-induced mutagens.
Authors:
L F Bjeldanes; M M Morris; J S Felton; S Healy; D Stuermer; P Berry; H Timourian; F T Hatch
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association     Volume:  20     ISSN:  0278-6915     ISO Abbreviation:  Food Chem. Toxicol.     Publication Date:  1982 Aug 
Date Detail:
Created Date:  1982-12-16     Completed Date:  1982-12-16     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8207483     Medline TA:  Food Chem Toxicol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  365-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cattle
Dairy Products / analysis
Dietary Proteins / analysis*
Fabaceae / analysis
Hot Temperature*
Meat / analysis
Mutagenicity Tests
Mutagens / analysis*
Plants, Medicinal
Salmonella typhimurium / genetics
Sheep
Shellfish / analysis
Chemical
Reg. No./Substance:
0/Dietary Proteins; 0/Mutagens

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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