Document Detail


Mutagenicity of wood smoke condensates in the Salmonella/microsome assay.
MedLine Citation:
PMID:  1881415     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Smoke condensates of woods used for food preservation and aromatization in Nigeria were tested for mutagenic activity using Salmonella typhimurium TA98 and TA100. The woods were: white mangrove (Avicennia nitida), red mangrove (Rhizophora racemosa), mahogany Khaya sp.), abura (Mitragyna ciliata), alstonia (Alstonia boonei) and black afara (Terminalia ivorensis). Cigarette tar was tested for comparison. The condensates induced dose-dependent increases in the number of His+ revertants mainly with S9 mix. With the exception of mahogany and cigarette smoke condensate, the smoke condensates induced more revertants/microgram condensate in TA100 than in TA98. The number of revertants/microgram condensate ranged between 0.04 and 0.9 for the wood smoke condensates and was 0.12 for the cigarette smoke in TA100. The range was between 0.1 and 0.30 for the wood smoke condensates and 0.18 revertants/microgram condensate for cigarette smoke condensate in TA98. Concentrations of 7 polycyclic aromatic hydrocarbons (PAHs) in the condensates were determined namely, pyrene, benzo[a]pyrene, benz[a]anthracene, benzo[k]fluoranthene, benzo[b]chrysene, benzo[g,h,i]perylene and dibenzo[a,e]pyrene. The condensates contained varying concentrations of the individual PAHs and those with higher concentrations generally showed greater mutagenic activities. However, the order of mutagenic potency in the bacterial strains differed from the order of PAH concentrations, which were lower than the concentrations at which they are reported to induce mutations. When 6 of the PAHs were mixed in the concentrations in which they were found in the individual condensates, the mixtures did not induce mutation so that the contribution of the PAHs to the mutagenic activities of the condensates could not be determined.
Authors:
A O Asita; M Matsui; T Nohmi; A Matsuoka; M Hayashi; M Ishidate; T Sofuni; M Koyano; H Matsushita
Related Documents :
18928295 - Impact of food disinfection on beneficial biothiol contents in strawberry.
11846285 - Some polycyclic aromatic hydrocarbons in vegetables from northern china.
17158795 - Integrated model shows that atmospheric brown clouds and greenhouse gases have reduced ...
17310695 - Ammonia emission controls as a cost-effective strategy for reducing atmospheric particu...
6484015 - Phase shifts of circadian rhythms in activity entrained to food access.
20936055 - Variable selection and updating in model-based discriminant analysis for high dimension...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Mutation research     Volume:  264     ISSN:  0027-5107     ISO Abbreviation:  Mutat. Res.     Publication Date:  1991 Sep 
Date Detail:
Created Date:  1991-10-03     Completed Date:  1991-10-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0400763     Medline TA:  Mutat Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  7-14     Citation Subset:  IM    
Affiliation:
National Institute of Hygienic Sciences, Tokyo, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Microsomes
Mutagenicity Tests
Mutagens*
Plants, Toxic
Polycyclic Compounds / toxicity*
Salmonella typhimurium / genetics
Smoke*
Tobacco
Wood*
Chemical
Reg. No./Substance:
0/Mutagens; 0/Polycyclic Compounds; 0/Smoke

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Simultaneous micronucleus and chromosome aberration assessment in the rat.
Next Document:  Correlations between antepartum maternal metabolism and child intelligence.