| Mutagenic and genotoxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin, a review. | |
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MedLine Citation:
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PMID: 3540643 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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2,3,7,8-Tetrachlorodibenzo-p-dioxin is one of the most toxic and highly stable compounds known in the environment. Due to uncontrolled exothermic reactions during manufacture of 2,4,5-T and other chlorophenoxy compounds, TCDD is released in the environment. The importance of determining the hazards to human health from dioxin became apparent because of its severe adverse health effects. 'Agent Orange' which is a mixture of 2,4,5-T and 2,4-D has been extensively used during the late Vietnam War. In this review an attempt has been made to evaluate the mutagenic and genotoxic effects of 2,3,7,8-TCDD as known at present. |
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Authors:
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A K Giri |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Mutation research Volume: 168 ISSN: 0027-5107 ISO Abbreviation: Mutat. Res. Publication Date: 1986 Nov |
Date Detail:
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Created Date: 1987-02-19 Completed Date: 1987-02-19 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0400763 Medline TA: Mutat Res Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 241-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Chromosome Aberrations Dioxins / pharmacology* Humans Mutagenicity Tests Mutagens* Mutation* Salmonella typhimurium / drug effects Tetrachlorodibenzodioxin / pharmacology*, toxicity |
| Chemical | |
Reg. No./Substance:
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0/Dioxins; 0/Mutagens; 1746-01-6/Tetrachlorodibenzodioxin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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