| Mutagenic activity of the feces of rats following oral administration of tartrazine. | |
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MedLine Citation:
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PMID: 3307706 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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After oral administration of the azo dye tartrazine, bile and feces of treated rats were investigated for mutagenicity using the Ames test with Salmonella typhimurium strains TA 98 and TA 100 with and without metabolic activation. In the presence of S 9-mix fecal extracts developed a weak but reproducible dose-related response in strain TA 100. In bile no metabolites exerting mutagenic activity were found. |
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Authors:
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R Münzner; J Wever |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Archives of toxicology Volume: 60 ISSN: 0340-5761 ISO Abbreviation: Arch. Toxicol. Publication Date: 1987 Jun |
Date Detail:
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Created Date: 1987-10-21 Completed Date: 1987-10-21 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0417615 Medline TA: Arch Toxicol Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 328-30 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Azo Compounds / toxicity* Bile / analysis Feces / analysis* Male Mutagenicity Tests Mutagens* Rats Rats, Inbred Strains Salmonella typhimurium / genetics Tartrazine / metabolism, toxicity* |
| Chemical | |
Reg. No./Substance:
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0/Azo Compounds; 0/Mutagens; 1934-21-0/Tartrazine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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