| Musculoskeletal syndromes associated with acne. | |
| | |
MedLine Citation:
|
PMID: 1828308 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The acne conglobata (AC)-, acne fulminans (AF)-, and isotretinoin-associated musculoskeletal syndromes are three distinct clinical entities. The AC-associated musculoskeletal syndrome occurs primarily in black men over the age of 22, who develop sacroilitis with or without a peripheral arthropathy. In contrast, the AF-associated musculoskeletal syndrome is found almost exclusively in white male teenagers. Fever, weight loss, and arthralgias are prominent components of this syndrome. A unique feature of the AF-associated musculoskeletal syndrome is osteolytic lesions that occur most frequently in the clavicle, sternum, long bones, and ilium. The isotretinoin-associated musculoskeletal syndrome occurs with equal frequency in male and female acne patients. Mild, transient myalgias and arthralgias are very common and do not require discontinuation of isotretinoin therapy. Asymptomatic, small, hyperostotic lesions of the spine occur in approximately 10% of acne patients with the isotretinoin-associated musculoskeletal syndrome. |
| | |
Authors:
|
R H Knitzer; B W Needleman |
Related Documents
:
|
995018 - Pseudohypoparathyroidism associated with cri du chat syndrome. 9744638 - Drop episodes in coffin-lowry syndrome: exaggerated startle responses treated with clon... 20144108 - Sjögren's syndrome associated with vitamin b(12) deficiency. 9633758 - Unilateral neglect: a common but heterogeneous syndrome. 2371808 - Malignant hyperthermia: the clinical syndrome. 8163858 - Lesch-nyhan syndrome: successful prevention of lower lip ulceration caused by self-muti... |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Review |
Journal Detail:
|
Title: Seminars in arthritis and rheumatism Volume: 20 ISSN: 0049-0172 ISO Abbreviation: Semin. Arthritis Rheum. Publication Date: 1991 Feb |
Date Detail:
|
Created Date: 1991-07-11 Completed Date: 1991-07-11 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 1306053 Medline TA: Semin Arthritis Rheum Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 247-55 Citation Subset: IM |
Affiliation:
|
Department of Medicine, University of Maryland, Baltimore 21201. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acne Vulgaris
/
complications*,
drug therapy,
pathology Adolescent Adult Bone Diseases / chemically induced, complications*, pathology Female Humans Isotretinoin / adverse effects, therapeutic use Male Middle Aged Muscular Diseases / chemically induced, complications*, pathology Syndrome |
| Chemical | |
Reg. No./Substance:
|
4759-48-2/Isotretinoin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Histamine and the stomach: chemical histamine assays.
Next Document: Comparison of propofol and thiopentone as induction agents for laparoscopy.