Document Detail

Musculoskeletal neoplasms: fast low-angle shot MR imaging with and without Gd-DTPA.
MedLine Citation:
PMID:  2367666     Owner:  NLM     Status:  MEDLINE    
In 121 patients, image contrast and contrast-to-noise ratios (C/Ns) obtained with gadolinium diethylene-triaminepentaacetic acid (DTPA)-enhanced and nonenhanced fast low-angle shot (FLASH) sequences were compared with those achieved with spin-echo (SE) sequences. Among FLASH sequences, contrast between neoplasms and muscle was sufficient with a flip angle of 90 degrees following administration of Gd-DTPA but was 61% lower than that with the T2-weighted SE sequence. High contrast levels were obtained between tumors and bone marrow or fat in sclerotic, calcified, and fibrotic lesions with the use of a flip angle of 90 degrees and in lytic lesions with a flip angle of 10 degrees, reaching 66% of the contrast level obtained with the T1-weighted SE sequence. C/N between tumor and surrounding tissue was always significantly lower with FLASH sequences than with the ideal SE sequences usually used for tumor delineation. Thus, a replacement of the T2-weighted SE sequences by FLASH sequences cannot be recommended. A replacement of the T1-weighted SE sequences by FLASH sequences seems possible but does not significantly reduce examination time.
R Erlemann; P Vassallo; G Bongartz; H Müller-Miny; E Rummeny; U Stöber; P E Peters
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiology     Volume:  176     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1990 Aug 
Date Detail:
Created Date:  1990-08-16     Completed Date:  1990-08-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  489-95     Citation Subset:  AIM; IM    
Department of Clinical Radiology, Westfälische Wilhelms-Universität, Münster, Federal Republic of Germany.
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MeSH Terms
Aged, 80 and over
Bone Neoplasms / diagnosis*
Contrast Media
Gadolinium DTPA
Magnetic Resonance Imaging* / methods
Middle Aged
Muscular Diseases / diagnosis*
Organometallic Compounds / diagnostic use*
Pentetic Acid / diagnostic use*
Soft Tissue Neoplasms / diagnosis*
Reg. No./Substance:
0/Contrast Media; 0/Organometallic Compounds; 67-43-6/Pentetic Acid; 80529-93-7/Gadolinium DTPA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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