Document Detail

Muscle wastage in heart failure: orphan of the heart failure.
MedLine Citation:
PMID:  18457888     Owner:  NLM     Status:  MEDLINE    
The patients with heart failure (HF) often exhibit some degree of muscle wasting restricted to the lower limbs. This loss of tissue may become more extensive in some patients, usually when their HF is more advanced, and may affect all body compartments. The underlying metabolic causes are very complex and differ from patient to patient. Three essential contributors are dietary deficiency and loss of nutrients through the digestive tract and metabolic dysfunction. The development of cachexia is an ominous sign and new drugs will be added into our therapeutic armamentarium to fight against cardiac cachexia in the near-future.
Turgay Celik; Atila Iyisoy; Murat Celik; U Cagdas Yuksel; Ersoy Isik
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Publication Detail:
Type:  Letter     Date:  2008-05-05
Journal Detail:
Title:  International journal of cardiology     Volume:  135     ISSN:  1874-1754     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-06-15     Completed Date:  2009-09-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  233-6     Citation Subset:  IM    
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MeSH Terms
Cachexia / complications*,  metabolism,  pathology*
Heart Failure / complications*,  metabolism
Muscular Atrophy / etiology*,  metabolism,  pathology*
Comment In:
Int J Cardiol. 2009 Jun 26;135(2):236-7   [PMID:  18678416 ]

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