| Muscle ultrasonography to predict survival in amyotrophic lateral sclerosis. | |
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MedLine Citation:
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PMID: 20392981 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The authors assessed the prognostic value of muscle ultrasonography in 31 patients with amyotrophic lateral sclerosis (ALS) and compared it with accepted prognostic variables like functional capacity (measured with the Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)) and muscle strength. Each patient was examined once. The following ultrasonography parameters were determined: muscle thickness, echo intensity (EI) and the presence of fasciculations. Correlations between baseline measurements, preslope values and survival were calculated. EI, disease duration, muscle strength preslope and ALSFRS-R preslope correlated with survival. Using a stepwise multivariate analysis, the combination of EI preslope and ALSFRS-R preslope was shown to have the best predictive value for survival. |
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Authors:
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Ilse Mp Arts; Sebastiaan Overeem; Sigrid Pillen; Helenius Jurgen Schelhaas; Machiel J Zwarts |
Publication Detail:
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Type: Journal Article Date: 2010-04-14 |
Journal Detail:
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Title: Journal of neurology, neurosurgery, and psychiatry Volume: 82 ISSN: 1468-330X ISO Abbreviation: J. Neurol. Neurosurg. Psychiatr. Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-04-08 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2985191R Medline TA: J Neurol Neurosurg Psychiatry Country: England |
Other Details:
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Languages: eng Pagination: 552-4 Citation Subset: IM |
Affiliation:
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Department of Neurology, Donders Institute for Neuroscience, Radboud University Nijmegen Medical Centre, PO Box 9101, Nijmegen 6500 HB, The Netherlands; HJ.Schelhaas@neuro.umcn.nl. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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