Document Detail

Muscle size and strength are increased following walk training with restricted venous blood flow from the leg muscle, Kaatsu-walk training.
MedLine Citation:
PMID:  16339340     Owner:  NLM     Status:  MEDLINE    
Previous studies have shown that low-intensity resistance training with restricted muscular venous blood flow (Kaatsu) causes muscle hypertrophy and strength gain. To investigate the effects of daily physical activity combined with Kaatsu, we examined the acute and chronic effects of walk training with and without Kaatsu on MRI-measured muscle size and maximum dynamic (one repetition maximum) and isometric strength, along with blood hormonal parameters. Nine men performed Kaatsu-walk training, and nine men performed walk training alone (control-walk). Training was conducted two times a day, 6 days/wk, for 3 wk using five sets of 2-min bouts (treadmill speed at 50 m/min), with a 1-min rest between bouts. Mean oxygen uptake during Kaatsu-walk and control-walk exercise was 19.5 (SD 3.6) and 17.2 % (SD 3.1) of treadmill-determined maximum oxygen uptake, respectively. Serum growth hormone was elevated (P < 0.01) after acute Kaatsu-walk exercise but not in control-walk exercise. MRI-measured thigh muscle cross-sectional area and muscle volume increased by 4-7%, and one repetition maximum and maximum isometric strength increased by 8-10% in the Kaatsu-walk group. There was no change in muscle size and dynamic and isometric strength in the control-walk group. Indicators of muscle damage (creatine kinase and myoglobin) and resting anabolic hormones did not change in both groups. The results suggest that the combination of leg muscle blood flow restriction with slow-walk training induces muscle hypertrophy and strength gain, despite the minimal level of exercise intensity. Kaatsu-walk training may be a potentially useful method for promoting muscle hypertrophy, covering a wide range of the population, including the frail and elderly.
Takashi Abe; Charles F Kearns; Yoshiaki Sato
Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't     Date:  2005-12-08
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  100     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-04-14     Completed Date:  2006-08-10     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol (1985)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1460-6     Citation Subset:  IM    
Department of Exercise and Sport Science, Tokyo Metropolitan University, University of Tokyo, Tokyo, Japan.
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MeSH Terms
Creatine Kinase / analysis
Exercise Test
Growth Hormone / blood
Hydrocortisone / blood
Hypertrophy / physiopathology
Leg / blood supply*,  pathology,  physiology*
Magnetic Resonance Imaging
Muscle, Skeletal / anatomy & histology,  blood supply,  pathology*,  physiology*
Oxygen Consumption / physiology
Physical Endurance / physiology
Physical Exertion / physiology*
Regional Blood Flow / physiology
Signal Transduction / physiology
Walking / physiology*
Reg. No./Substance:
50-23-7/Hydrocortisone; 9002-72-6/Growth Hormone; EC Kinase
Comment In:
J Appl Physiol (1985). 2006 May;100(5):1443-4   [PMID:  16614363 ]
Erratum In:
J Appl Physiol. 2008 Apr;104(4):1255

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