Document Detail


Muscle glycogen synthesis after exercise: effect of time of carbohydrate ingestion.
MedLine Citation:
PMID:  3132449     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The time of ingestion of a carbohydrate supplement on muscle glycogen storage postexercise was examined. Twelve male cyclists exercised continuously for 70 min on a cycle ergometer at 68% VO2max, interrupted by six 2-min intervals at 88% VO2max, on two separate occasions. A 25% carbohydrate solution (2 g/kg body wt) was ingested immediately postexercise (P-EX) or 2 h postexercise (2P-EX). Muscle biopsies were taken from the vastus lateralis at 0, 2, and 4 h postexercise. Blood samples were obtained from an antecubital vein before and during exercise and at specific times after exercise. Muscle glycogen immediately postexercise was not significantly different for the P-EX and 2P-EX treatments. During the first 2 h postexercise, the rate of muscle glycogen storage was 7.7 mumol.g wet wt-1.h-1 for the P-EX treatment, but only 2.5 mumol.g wet wt-1.h-1 for the 2P-EX treatment. During the second 2 h of recovery, the rate of glycogen storage slowed to 4.3 mumol.g wet wt-1.h-1 during treatment P-EX but increased to 4.1 mumol.g wet wt-1.h-1 during treatment 2P-EX. This rate, however, was still 45% slower (P less than 0.05) than that for the P-EX treatment during the first 2 h of recovery. This slower rate of glycogen storage occurred despite significantly elevated plasma glucose and insulin levels. The results suggest that delaying the ingestion of a carbohydrate supplement post-exercise will result in a reduced rate of muscle glycogen storage.
Authors:
J L Ivy; A L Katz; C L Cutler; W M Sherman; E F Coyle
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  64     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  1988 Apr 
Date Detail:
Created Date:  1988-07-15     Completed Date:  1988-07-15     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol (1985)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1480-5     Citation Subset:  IM; S    
Affiliation:
Department of Kinesiology and Health Education, University of Texas, Austin 78712.
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Glucose / metabolism
Dietary Carbohydrates*
Fatty Acids, Nonesterified / blood
Glycogen / biosynthesis*
Glycogen Synthase / metabolism
Humans
Insulin / blood
Kinetics
Male
Muscles / metabolism*
Physical Exertion*
Time Factors
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/Dietary Carbohydrates; 0/Fatty Acids, Nonesterified; 0/Insulin; 9005-79-2/Glycogen; EC 2.4.1.11/Glycogen Synthase

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