Document Detail


Muscle glycogen concentration during recovery after prolonged severe exercise in fasting subjects.
MedLine Citation:
PMID:  705238     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The influence of 12 h of fasting after prolonged severe exercise on the muscle glycogen concentration was studed in 5 normal subjects. The subjects exercised in the post absorptive state at 70% of max. Vo2 till exhaustion, then rested for 12 h. No food was allowed during recovery. Blood samples and muscle biopsies were obtained before exercise, immediately after the cessation of exercise, and after 2, 4, 6, 9 and 12 h of recovery. Muscle glycogen content decreased from 70.4 +/- 3.0 to 21.6 +/- 3.9 mmol glucosyl units/kg w.w. in response to exercise. After 4 h of recovery muscle glycogen had increased to 28.8 +/- 3.6 mmol glucosyl units/kg (P less than 0.025). During the next 8 h of recovery no further increase in glycogen concentration was observed. Mean plasma glucose concentration was observed. Mean plasma glucose concentration decreased from 5.25 +/- 0.16 to 4.37 +/- 0.18 mmol/l during exercise (P less than 0.001). No change in the plasma glucose level was observed during recovery. Immunoreactive insulin (IRI) concentration decreased from 15.9 +/- 1.0 to 10.2 +/- 0.5 micromicron/ml (P less than 0.001) during exercise, and remained at this level during recovery. It is concluded that some muscle glycogen repletion may occur after prolonged, severe exercise even under fasting conditions. It is suggested that this may proceed through an increased hepatic gluconeogenesis.
Authors:
S Maehlum; L Hermansen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Scandinavian journal of clinical and laboratory investigation     Volume:  38     ISSN:  0036-5513     ISO Abbreviation:  Scand. J. Clin. Lab. Invest.     Publication Date:  1978 Oct 
Date Detail:
Created Date:  1978-12-20     Completed Date:  1978-12-20     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0404375     Medline TA:  Scand J Clin Lab Invest     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  557-60     Citation Subset:  IM; S    
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Glucose / analysis
Fasting*
Glycogen / metabolism*
Humans
Insulin / blood
Male
Muscles / metabolism*
Physical Exertion*
Time Factors
Chemical
Reg. No./Substance:
0/Blood Glucose; 11061-68-0/Insulin; 9005-79-2/Glycogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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