Document Detail


Muscle glucose transporter (GLUT 4) gene expression during exercise.
MedLine Citation:
PMID:  11064847     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Among the many effects of exercise is the induction of glucose transporter (GLUT 4) expression in skeletal muscle. In this review, we examine the intracellular signals that may mediate the exercise-induced increase in GLUT4 gene transcription. This induction is likely to be dependent upon intracellular calcium concentrations and the energy charge of the muscle.
Authors:
P S MacLean; D Zheng; G L Dohm
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Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  Exercise and sport sciences reviews     Volume:  28     ISSN:  0091-6331     ISO Abbreviation:  Exerc Sport Sci Rev     Publication Date:  2000 Oct 
Date Detail:
Created Date:  2001-02-15     Completed Date:  2001-02-15     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0375434     Medline TA:  Exerc Sport Sci Rev     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  148-52     Citation Subset:  IM    
Affiliation:
Department of Biochemistry, School of Medicine, East Carolina University, Greenville, North Carolina 27858, USA.
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MeSH Terms
Descriptor/Qualifier:
AMP-Activated Protein Kinases
Animals
Calcineurin / metabolism,  physiology
Calcium / metabolism,  physiology
Calmodulin / metabolism,  physiology
DNA-Binding Proteins / metabolism
Energy Metabolism
Exercise / physiology*
Gene Expression Regulation
Glucose / metabolism
Homeostasis
Humans
Mice
Mice, Transgenic
Monosaccharide Transport Proteins / genetics*
Multienzyme Complexes / metabolism
Muscle Contraction / physiology
Muscle, Skeletal / enzymology,  metabolism*,  physiology
Myogenic Regulatory Factors
Protein Kinase C / metabolism
Protein-Serine-Threonine Kinases / metabolism
RNA, Messenger / analysis
Rats
Signal Transduction
Time Factors
Transcription Factors / metabolism
Transcription, Genetic
Chemical
Reg. No./Substance:
0/Calmodulin; 0/DNA-Binding Proteins; 0/Monosaccharide Transport Proteins; 0/Multienzyme Complexes; 0/Myogenic Regulatory Factors; 0/RNA, Messenger; 0/Transcription Factors; 0/myocyte-specific enhancer-binding factor 2; 50-99-7/Glucose; 7440-70-2/Calcium; EC 2.7.11.1/AMP-Activated Protein Kinases; EC 2.7.11.1/Protein-Serine-Threonine Kinases; EC 2.7.11.13/Protein Kinase C; EC 3.1.3.16/Calcineurin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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