Document Detail


Muscle changes in patients with varicose veins.
MedLine Citation:
PMID:  146395     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Gastrocnemius muscle specimens from 19 patients with varicose veins without clinical neuropathy were examined with a light microscope after staining fresh-frozen sections with modified Gomori trichrome and after histochemical reactions for NADH diaphorase, ATPases and phosphorylase. Only four muscle specimens from these 19 patients were regarded as completely normal. In five of the patients (26 per cent) a combination of fiber type grouping and small-group atrophy, and in nine patients (47 per cent) fiber type grouping with occasional small angulated fibers were observed. These changes were less frequent in nine biopsies from brain-death control patients (11 per cent). Various forms of abnormalities in the distribution of NADH diaphorase were seen in 13 patients with varicose veins (68 per cent) and in one of the controls (11 per cent). Necrosis and phagocytosis of the muscle fibers were present in three biopsies from patients with varicose veins (16 per cent) and in one of the controls (11 per cent).
Authors:
J Mäkitie
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta pathologica et microbiologica Scandinavica. Section A, Pathology     Volume:  85     ISSN:  0365-4184     ISO Abbreviation:  Acta Pathol Microbiol Scand A     Publication Date:  1977 Nov 
Date Detail:
Created Date:  1978-03-21     Completed Date:  1978-03-21     Revised Date:  2009-06-04    
Medline Journal Info:
Nlm Unique ID:  7508468     Medline TA:  Acta Pathol Microbiol Scand A     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  864-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adenosine Triphosphatases / metabolism
Adult
Aged
Dihydrolipoamide Dehydrogenase / metabolism
Female
Humans
Male
Middle Aged
Muscles / enzymology,  pathology
Muscular Atrophy
Muscular Diseases / enzymology,  etiology*,  pathology
Phosphorylases / metabolism
Varicose Veins / complications*,  enzymology,  pathology
Chemical
Reg. No./Substance:
EC 1.8.1.4/Dihydrolipoamide Dehydrogenase; EC 2.4.1.-/Phosphorylases; EC 3.6.1.-/Adenosine Triphosphatases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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