Document Detail

Murray valley encephalitis mimicking herpes simplex encephalitis.
MedLine Citation:
PMID:  16169227     Owner:  NLM     Status:  MEDLINE    
We describe a patient with serologically proven Murray Valley encephalitis (MVE), whose presentation was clinically and radiologically characteristic of Herpes simplex encephalitis (HSE). The reports of MRI abnormalities in MVE, and the closely related Japanese Encephalitis and West Nile virusii are mostly of bilateral thalamic or grey matter involvement. The MRI scan findings in this case instead showed the typical temporal lobe changes of HSE. Our case report highlights that MVE can mimic HSE, both clinically and radiologically. Therefore it is important to collect an accurate and detailed travel history from patients where there is a risk of exposure to MVE virus. If suspected, antibody testing of serum and CSF, and CSF for MVE-RNA if available, should be undertaken. This case also highlights the potential under-diagnosis of Murray Valley encephalitis.
S H Wong; D W Smith; M J Fallon; A G Kermode
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia     Volume:  12     ISSN:  0967-5868     ISO Abbreviation:  J Clin Neurosci     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-10-03     Completed Date:  2006-05-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9433352     Medline TA:  J Clin Neurosci     Country:  Scotland    
Other Details:
Languages:  eng     Pagination:  822-4     Citation Subset:  IM    
Department of Neurology and Clinical Neurophysiology, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, WA 6009, Australia.
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MeSH Terms
Diagnosis, Differential
Encephalitis Virus, Murray Valley*
Encephalitis, Arbovirus / diagnosis*,  radiography,  virology*
Encephalitis, Herpes Simplex*
Magnetic Resonance Imaging / methods

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