Document Detail

Murine typhus endocarditis.
MedLine Citation:
PMID:  1631693     Owner:  NLM     Status:  MEDLINE    
We have described a 28-year-old male sheepfarmer who had fever, headache, chills, malaise, and aortic insufficiency. Echocardiography revealed a tricuspid aortic valve with a large vegetation on the right cusp, an enlarged left ventricle, and diastolic flutter of the mitral valve. Repeated blood cultures were negative. Seroconversion of IgG and IgM to Rickettsia typhi was found on the 13th day of hospitalization. The patient was treated with tetracycline for 1 year and remained afebrile and free of symptoms for 9 months, when he was lost to follow-up. IgM and IgG fluorescent antibodies to R typhi remained positive during 8 months of the follow-up period. We believe this to be the second reported case of endocarditis due to R typhi and the first not treated surgically.
A E Buchs; R Zimlichman; E Sikuler; B Goldfarb
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Southern medical journal     Volume:  85     ISSN:  0038-4348     ISO Abbreviation:  South. Med. J.     Publication Date:  1992 Jul 
Date Detail:
Created Date:  1992-08-14     Completed Date:  1992-08-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  751-3     Citation Subset:  AIM; IM    
Department of Medicine, Soroka Medical Center, Beer Sheva, Israel.
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MeSH Terms
Endocarditis, Bacterial / drug therapy,  microbiology*
Tetracycline / therapeutic use
Typhus, Endemic Flea-Borne / diagnosis*,  drug therapy
Reg. No./Substance:

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