Document Detail


Murine microvideo endoscopy of the colonic microcirculation.
MedLine Citation:
PMID:  17612562     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Natural orifice endoscopy in small animal models has been limited in the past by instrument size and optical performance. In this report, we investigate the feasibility of using a recently developed microvideo endoscopy system to evaluate the colon microcirculation. Using a murine model of acute colitis, microvideo endoscopy was useful in mapping the topography of inflammation as well as identifying relevant structures in the microcirculation. We conclude that natural orifice endoscopy is a useful method for the minimally invasive longitudinal assessment of the colonic mucosal microcirculation.
Authors:
Dino J Ravnic; Moritz A Konerding; Harold T Huss; Tanja Wolloscheck; Juan P Pratt; Steven J Mentzer
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2007-07-05
Journal Detail:
Title:  The Journal of surgical research     Volume:  142     ISSN:  0022-4804     ISO Abbreviation:  J. Surg. Res.     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-08-24     Completed Date:  2007-10-02     Revised Date:  2011-09-26    
Medline Journal Info:
Nlm Unique ID:  0376340     Medline TA:  J Surg Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  97-103     Citation Subset:  IM    
Affiliation:
Department of Surgery, Brigham & Women's Hospital, Boston, Massachusetts 02115, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Capillaries / pathology
Colitis / pathology
Colon / blood supply*,  pathology
Colonoscopy / methods,  veterinary
Disease Models, Animal
Endoscopy, Gastrointestinal / methods*,  veterinary*
Intestinal Mucosa / blood supply
Male
Mice
Mice, Inbred BALB C
Microcirculation
Video Recording / methods*
Grant Support
ID/Acronym/Agency:
HL47078/HL/NHLBI NIH HHS; HL75426/HL/NHLBI NIH HHS; R01 HL047078-13/HL/NHLBI NIH HHS; R01 HL075426-04/HL/NHLBI NIH HHS
Comments/Corrections

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